Incivek Uses

15 January 2013 | Incivek

Incivek Uses:

Before taking Incivek

You should not use Incivek if you are allergic to telaprevir.

To make sure you can safely take Incivek, tell your doctor if you have any of these other conditions:

  • hepatitis B or liver problems other than hepatitis C;
  • kidney disease (or if you are on dialysis);
  • anemia (lack of red blood cells);
  • if you have had an organ transplant;
  • HIV or AIDS;
  • a history of gout; or
  • if you have ever used medicine to treat hepatitis in the past and it did not work.

There are many other drugs that can cause serious or life threatening medical problems if you take them together with Incivek. The following drugs should not be used while you are taking Incivek:

  • alfuzosin (Uroxatral);
  • atorvastatin (Lipitor, Caduet), lovastatin (Mevacor, Altoprev, Advicor), or simvastatin (Zocor, Simcor, Vytorin, Juvisync);
  • cisapride (Propulsid);
  • pimozide (Orap);
  • midazolam (Versed) or triazolam (Halcion);
  • sildenafil (Revatio) or tadalafil (Adcirca) when used to treat pulmonary arterial hypertension;
  • St. John’s wort;
  • rifampin (Rifadin, Rifater, Rifamate); or
  • ergonovine, ergotamine (Ergomar, Cafergot, Migergot), dihydroergotamine (D.H.E. 45, Migranal), or methylergonovine (Methergine).

FDA pregnancy category X. Incivek is given together with interferon alfa and ribavirin. Although Incivek is not expected to harm an unborn baby, ribavirin is known to cause birth defects or death in an unborn baby. Do not use this combination of drugs if you are pregnant, or if you are a man and your sexual partner is pregnant. If you are a woman, you may need to have a negative pregnancy test before using these medications and every month during your treatment.

  • Use at least 2 non-hormonal forms of birth control while either sexual partner is using Incivek with interferon alfa and ribavirin. Keep using 2 forms of birth control for at least 6 months after treatment ends.
  • If you are a woman, do not use Incivek with interferon alfa and ribavirin if you are pregnant.
  • If you are a man, do not use Incivek with interferon alfa and ribavirin if your sexual partner is pregnant. An unborn baby could also be harmed if a man fathers the child while he is taking ribavirin.
  • Hormonal contraception (such as birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during your treatment. Ask your doctor about using a non-hormone method of birth control (such as a condom, intrauterine device (IUD), diaphragm with spermicide) to prevent pregnancy while taking Incivek.
  • Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Incivek with interferon alfa and ribavirin.

It is not known whether telaprevir passes into breast milk or if it could harm a nursing baby. Do not breast-feed a baby while taking Incivek.

How should I take Incivek?

Take Incivek exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Do not take Incivek as your only medication to treat hepatitis C. Incivek must be used in combination with peginterferon alfa and ribavirin. Your disease may become resistant to Incivek if you do not take it in combination with other medicines your doctor has prescribed.

This combination treatment is usually given for 12 to 48 weeks. The usual dose of Incivek is 2 tablets taken 3 times per day, every 7 to 9 hours. Follow your doctor’s instructions.

Take Incivek within 30 minutes after eating a meal or snack that contains about 20 grams of fat. Always take Incivek with food. Examples of snacks that contain about 20 grams of fat include: A bagel and cream cheese, 3 tablespoons of peanut butter, 2 ounces of American or cheddar cheese, 2 ounces of potato chips, a half-cup of nuts or trail mix, or 1 cup of ice cream.

Your total daily dose of 6 tablets is contained in a single blister strip of Incivek. A package of Incivek contains 4 cartons of 7 blister strips for a 4-week supply.

To be sure this medicine is helping your condition and is not causing harmful effects, your blood will need to be tested often. Visit your doctor regularly.

If you need surgery, tell the surgeon ahead of time that you are using Incivek. You may need to stop using the medicine for a short time. Do not stop taking this medication unless your doctor tells you to. If you stop taking Incivek for any reason, do not start taking it again without your doctor’s advice.

Store Incivek at room temperature away from moisture and heat.


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